研究・業績

2014年

1. Ito K, Yotsuyanagi H, Yatsuhashi H, Karino Y, Takikawa Y, Saito T, Arase Y, Imazeki F, Kurosaki M, Umemura T, Ichida T, Toyoda H, Yoneda M, Mita E, Yamamoto K, Michitaka K, Maeshiro T, Tanuma J, Tanaka Y, Sugiyama M, Murata K, Masaki N, Mizokami MRisk Factors for Long-Term Persistence of Serum Hepatitis B Surface Antigen Following Acute Hepatitis B Virus Infection in Japanese Adults.   Hepatology 59 (1): 89-97 2014.01

2. Murata K, Sugiyama M, Kimura T, Yoshio S, Kanto T, Kirikae I, Saito H, Aoki Y, Hiramine S, Matsui T, Ito K, Korenaga M, Imamura M, Masaki N, Mizokami MEx Vivo Induction of Ifn-Lambda3 by a Tlr7 Agonist Determines Response to Peg-Ifn/Ribavirin Therapy in Chronic Hepatitis C Patients.   J Gastroenterol 49 (1): 126-37 2014.01

3. Nishida N, Sawai H, Kashiwase K, Minami M, Sugiyama M, Seto WK, Yuen MF, Posuwan N, Poovorawan Y, Ahn SH, Han KH, Matsuura K, Tanaka Y, Kurosaki M, Asahina Y, Izumi N, Kang JH, Hige S, Ide T, Yamamoto K, Sakaida I, Murawaki Y, Itoh Y, Tamori A, Orito E, Hiasa Y, Honda M, Kaneko S, Mita E, Suzuki K, Hino K, Tanaka E, Mochida S, Watanabe M, Eguchi Y, Masaki N, Murata K, Korenaga M, Mawatari Y, Ohashi J, Kawashima M, Tokunaga K, Mizokami MNew Susceptibility and Resistance Hla-Dp Alleles to Hbv-Related Diseases Identified by a Trans-Ethnic Association Study in Asia.   PLoS One 9 (2): e86449 2014.02.10

4. Khudayberganova D, Sugiyama M, Masaki N, Nishida N, Mukaide M, Sekler D, Latipov R, Nataliya K, Dildora S, Sharapov S, Usmanova G, Raxmanov M, Musabaev E, Mizokami MIl28b Polymorphisms and Clinical Implications for Hepatitis C Virus Infection in Uzbekistan.   PLoS One 9 (3): e93011 2014.03

5. Matsuura K, Tanaka Y, Watanabe T, Fujiwara K, Orito E, Kurosaki M, Izumi N, Sakamoto N, Enomoto N, Yatsuhashi H, Kusakabe A, Shinkai N, Nojiri S, Joh T, Mizokami MItpa Genetic Variants Influence Efficacy of Peg-Ifn/Rbv Therapy in Older Patients Infected with Hcv Genotype 1 and Favourable Il28b Type.   J Viral Hepat 21 (7): 466-74 2014.07

6. Nishida N, Noguchi M, Kuroda K, Ueda M.  A Design for the Control of Apoptosis in Genetically Modified Saccharomyces Cerevisiae.   Biosci Biotechnol Biochem 78 (2): 358-62 2014.07

7. Sato I, Shimbo T, Kawasaki Y, Mizokami M, Masaki NEfficacy and Safety of Interferon Treatment in Elderly Patients with Chronic Hepatitis C in Japan: A Retrospective Study Using the Japanese Interferon Database.   Hepatol Res[Epub ahead of print]: 2014.09.5

8. Mukaide M, Sugiyama M, Korenaga M, Murata K, Kanto T, Masaki N, Mizokami MHigh-Throughput and Sensitive Next-Generation Droplet Digital Pcr Assay for the Quantitation of the Hepatitis C Virus Mutation at Core Amino Acid 70.   J Virol Methods 207: 169-77 2014.10

9. Omata M, Nishiguchi S, Ueno Y, Mochizuki H, Izumi N, Ikeda F, Toyoda H, Yokosuka O, Nirei K, Genda T, Umemura T, Takehara T, Sakamoto N, Nishigaki Y, Nakane K, Toda N, Ide T, Yanase M, Hino K, Gao B, Garrison KL, Dvory-Sobol H, Ishizaki A, Omote M, Brainard D, Knox S, Symonds WT, McHutchison JG, Yatsuhashi H, Mizokami MSofosbuvir Plus Ribavirin in Japanese Patients with Chronic Genotype 2 Hcv Infection: An Open-Label, Phase 3 Trial.   J Viral Hepat 21 (11): 762-8 2014.11

10. Masaki N, Sugiyama M, Shimada N, Tanaka Y, Nakamuta M, Izumi N, Watanabe S, Tsubota A, Komatsu M, Masaki T, Enomoto N, Yoneda M, Murata K, Ito K, Koike K, Mizokami MPretreatment Prediction of the Outcome of Response-Guided Peginterferon-Alpha and Ribavirin Therapy for Chronic Hepatitis C.   J Gastroenterol Hepatol 29 (12): 1996-2005 2014.12

11. Aoki Y, Sugiyama M, Murata K, Yoshio S, Kurosaki M, Hashimoto S, Yatsuhashi H, Nomura H, Kang JH, Takeda T, Naito S, Kimura T, Yamagiwa Y, Korenaga M, Imamura M, Masaki N, Izumi N, Kage M, Mizokami M, Kanto TAssociation of Serum Ifn-Lambda with Inflammatory and Fibrosis Markers in Patients with Chronic Hepatitis C Virus Infection.   J Gastroenterol [Epub ahead of print]: 2014.12.14

共著論文

1. Sakakibara E, Takizawa R, Nishimura Y, Kawasaki S, Satomura Y, Kinoshita A, Koike S, Marumo K, Kinou M, Tochigi M, Nishida N, Tokunaga K, Eguchi S, Yamasaki S, Natsubori T, Iwashiro N, Inoue H, Takano Y, Takei K, Suga M, Yamasue H, Matsubayashi J, Kohata K, Shimojo C, Okuhata S, Kono T, Kuwabara H, Ishii-Takahashi A, Kawakubo Y, Kasai K.  Genetic Influences on Prefrontal Activation During a Verbal Fluency Task in Adults: A Twin Study Based on Multichannel near-Infrared Spectroscopy.   Neuroimage 85 Pt 1: 508-17 2014.01.15

2. Yamada R, Hiramatsu N, Oze T, Morishita N, Harada N, Miyazaki M, Yakushijin T, Miyagi T, Yoshida Y, Tatsumi T, Kanto T, Hayashi N, Takehara T.  Significance of Liver Stiffness Measurement by Acoustic Radiation Force Impulse (Arfi) among Hepatitis C Patients.   J Med Virol 86 (2): 241-7 2014.02

3. Fujiya K, Nagata N, Uchida T, Kobayakawa M, Asayama N, Akiyama J, Shimbo T, Igari T, Banerjee R, Nageshwar Reddy D, Mizokami M, Uemura N.  Different Gastric Mucosa and Caga Status of Patients in India and Japan Infected with Helicobacter Pylori.   Dig Dis Sci 59 (3): 631-7 2014.03

4. Kobayashi M, Sako A, Ogami T, Nishimura S, Asayama N, Yada T, Nagata N, Sakurai T, Yokoi C, Kobayakawa M, Yanase M, Masaki N, Takeshita N, Uemura N.  Validation of the 3-Day Rule for Stool Bacterial Tests in Japan.   Intern Med 53 (6): 533-9 2014.03

5. Nagata N, Niikura R, Aoki T, Shimbo T, Itoh T, Goda Y, Suda R, Yano H, Akiyama J, Yanase M, Mizokami M, Uemura N.  Increase in Colonic Diverticulosis and Diverticular Hemorrhage in an Aging Society: Lessons from a 9-Year Colonoscopic Study of 28,192 Patients in Japan.   Int J Colorectal Dis 29 (3): 379-85 2014.03

6. Nakano N, Kusumoto S, Tanaka Y, Ishida T, Takeuchi S, Takatsuka Y, Akinaga S, Mizokami M, Ueda R, Utsunomiya A.  Reactivation of Hepatitis B Virus in a Patient with Adult T-Cell Leukemia-Lymphoma Receiving the Anti-Cc Chemokine Receptor 4 Antibody Mogamulizumab.   Hepatol Res 44 (3): 354-7 2014.03

7. Xeuatvongsa A, Komada K, Kitamura T, Vongphrachanh P, Pathammavong C, Phounphenghak K, Sisouk T, Phonekeo D, Sengkeopaseuth B, Som-Oulay V, Ishii K, Wakita T, Sugiyama M, Hachiya M.  Chronic Hepatitis B Prevalence among Children and Mothers: Results from a Nationwide, Population-Based Survey in Lao People's Democratic Republic.   PLoS One 9 (2): e88829 2014.03

8. Hamada Y, Nagata N, Nishijima T, Shimbo T, Asayama N, Kishida Y, Sekine K, Tanaka S, Aoki T, Watanabe K, Akiyama J, Igari T, Mizokami M, Uemura N, Oka S.  Impact of Hiv Infection on Colorectal Tumors: A Prospective Colonoscopic Study of Asian Patients.   J Acquir Immune Defic Syndr 65 (3): 312-7 2014.03.1

9. Ocho M, Togayachi A, Iio E, Kaji H, Kuno A, Sogabe M, Korenaga M, Gotoh M, Tanaka Y, Ikehara Y, Mizokami M, Narimatsu H.  Application of a Glycoproteomics-Based Biomarker Development Method: Alteration in Glycan Structure on Colony Stimulating Factor 1 Receptor as a Possible Glycobiomarker Candidate for Evaluation of Liver Cirrhosis.   J Proteome Res 13 (3): 1428-37 2014.03.7

10. Oze T, Hiramatsu N, Yakushijin T, Miyazaki M, Iio S, Oshita M, Hagiwara H, Mita E, Inui Y, Hijioka T, Inada M, Tamura S, Yoshihara H, Inoue A, Imai Y, Miyagi T, Yoshida Y, Tatsumi T, Kanto T, Kasahara A, Hayashi N, Takehara T.  Using Early Viral Kinetics to Predict Antiviral Outcome in Response-Guided Pegylated Interferon Plus Ribavirin Therapy among Patients with Hepatitis C Virus Genotype 1.   J Gastroenterol 49 (4): 737-47 2014.04

11. Aiba Y, Harada K, Komori A, Ito M, Shimoda S, Nakamura H, Nagaoka S, Abiru S, Migita K, Ishibashi H, Nakanuma Y, Nishida N, Kawashima M, Tokunaga K, Yatsuhashi H, Nakamura M.  Systemic and Local Expression Levels of Tnf-Like Ligand 1a and Its Decoy Receptor 3 Are Increased in Primary Biliary Cirrhosis.   Liver Int 34 (5): 679-88 2014.05

12. Harada N, Hiramatsu N, Oze T, Morishita N, Yamada R, Hikita H, Miyazaki M, Yakushijin T, Miyagi T, Yoshida Y, Tatsumi T, Kanto T, Kasahara A, Oshita M, Mita E, Hagiwara H, Inui Y, Katayama K, Tamura S, Yoshihara H, Imai Y, Inoue A, Hayashi N, Takehara T.  Risk Factors for Hepatocellular Carcinoma in Hepatitis C Patients with Normal Alanine Aminotransferase Treated with Pegylated Interferon and Ribavirin.   J Viral Hepat 21 (5): 357-65 2014.05

13. Nakamura T, Sata M, Hiroishi K, Masaki N, Moriwaki H, Murawaki Y, Yatsuhashi H, Fujiyama S, Imawari M.  Contribution of Diuretic Therapy with Human Serum Albumin to the Management of Ascites in Patients with Advanced Liver Cirrhosis: A Prospective Cohort Study.   Mol Clin Oncol 2 (3): 349-355 2014.05

14. Ueta M, Kaniwa N, Sotozono C, Tokunaga K, Saito Y, Sawai H, Miyadera H, Sugiyama E, Maekawa K, Nakamura R, Nagato M, Aihara M, Matsunaga K, Takahashi Y, Furuya H, Muramatsu M, Ikezawa Z, Kinoshita S.  Independent Strong Association of Hla-a*02:06 and Hla-B*44:03 with Cold Medicine-Related Stevens-Johnson Syndrome with Severe Mucosal Involvement.   Sci Rep 4: 4862 2014.05

15. Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T.  Cyclosporin a and Its Analogs Inhibit Hepatitis B Virus Entry into Cultured Hepatocytes through Targeting a Membrane Transporter, Sodium Taurocholate Cotransporting Polypeptide (Ntcp).   Hepatology 59 (5): 1726-37 2014.05

16. Ishikane M, Watanabe K, Tsukada K, Nozaki Y, Yanase M, Igari T, Masaki N, Kikuchi Y, Oka S, Gatanaga H.  Acute Hepatitis C in Hiv-1 Infected Japanese Cohort: Single Center Retrospective Cohort Study.   PLoS One 9 (6): e100517 2014.06

17. Srilohasin P, Chaiprasert A, Tokunaga K, Nao N, Prammananan T.  Novel DNA Chip Based on a Modified Digitag2 Assay for High-Throughput Species Identification and Genotyping of Mycobacterium Tuberculosis Complex Isolates.   J Clin Microbiol 52 (6): 1962-8 2014.06

18. Morishita N, Hiramatsu N, Oze T, Harada N, Yamada R, Miyazaki M, Yakushijin T, Miyagi T, Yoshida Y, Tatsumi T, Kanto T, Takehara T.  Liver Stiffness Measurement by Acoustic Radiation Force Impulse Is Useful in Predicting the Presence of Esophageal Varices or High-Risk Esophageal Varices among Patients with Hcv-Related Cirrhosis.   J Gastroenterol 49 (7): 1175-82 2014.07

19. Nishino J, Sugiyama M, Nishida N, Tokunaga K, Mizokami M, Mano S.  The Interaction of a Single-Nucleotide Polymorphism with Age on Response to Interferon-Alpha and Ribavirin Therapy in Female Patients with Hepatitis C Infection.   J Med Virol 86 (7): 1130-3 2014.07

20. Akamatsu N, Sugawara Y, Kokudo N, Eguchi S, Fujiwara T, Ohdan H, Nagano H, Taketomi A, Kitagawa Y, Shimada M, Ku Y, Yanaga K, Shirabe K, Ikegami T, Mizokami M, Takeuchi M, Maehara Y.  Outcomes of Living Donor Liver Transplantation for Hepatitis C Virus-Positive Recipients in Japan: Results of a Nationwide Survey.   Transpl Int 27 (8): 767-74 2014.08

21. Kusumoto S, Tanaka Y, Mizokami M, Ueda R.  Strategy for Preventing Hepatitis B Reactivation in Patients with Resolved Hepatitis B Virus Infection after Rituximab-Containing Chemotherapy.   Hepatology 60 (2): 765-6 2014.08

22. Wada N, Yasunaka T, Ikeda F, Nishina S, Korenaga M, Hino K, Fujioka S, Osawa T, Itoshima T, Kawanaka M, Yamada G, Kariyama K, Takayama H, Kubota J, Morimoto Y, Mizushima T, Yamashita H, Tanioka H, Negoro Y, Toshimori J, Kobashi H, Hirano A, Itano Y, Takaki A, Yamamoto K.  Prevalence and Outcomes of Acute Hepatitis B in Okayama, Japan, 2006-2010.   Acta Med Okayama 68 (4): 243-7 2014.08

23. Kawasaki A, Furukawa H, Nishida N, Warabi E, Kondo Y, Ito S, Matsumoto I, Kusaoi M, Amano H, Suda A, Nagaoka S, Setoguchi K, Nagai T, Hirohata S, Shimada K, Sugii S, Okamoto A, Chiba N, Suematsu E, Ohno S, Katayama M, Okamoto A, Kono H, Tokunaga K, Takasaki Y, Hashimoto H, Sumida T, Tohma S, Tsuchiya N.  Association of Functional Polymorphisms in Interferon Regulatory Factor 2 (Irf2) with Susceptibility to Systemic Lupus Erythematosus: A Case-Control Association Study.   PLoS One 9 (10): e109764 2014.10

24. Nagata N, Niikura R, Aoki T, Shimbo T, Kishida Y, Sekine K, Tanaka S, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Mizokami M, Uemura N.  Colonic Diverticular Hemorrhage Associated with the Use of Nonsteroidal Anti-Inflammatory Drugs, Low-Dose Aspirin, Antiplatelet Drugs, and Dual Therapy.   J Gastroenterol Hepatol 29 (10): 1786-93 2014.10

25. Abe M, Miyake T, Kuno A, Imai Y, Sawai Y, Hino K, Hara Y, Hige S, Sakamoto M, Yamada G, Kage M, Korenaga M, Hiasa Y, Mizokami M, Narimatsu H.  Association between Wisteria Floribunda Agglutinin-Positive Mac-2 Binding Protein and the Fibrosis Stage of Non-Alcoholic Fatty Liver Disease.   J Gastroenterol [Epub ahead of print]: 2014.10.18

26. Awata T, Yamashita H, Kurihara S, Morita-Ohkubo T, Miyashita Y, Katayama S, Mori K, Yoneya S, Kohda M, Okazaki Y, Maruyama T, Shimada A, Yasuda K, Nishida N, Tokunaga K, Koike A.  A Genome-Wide Association Study for Diabetic Retinopathy in a Japanese Population: Potential Association with a Long Intergenic Non-Coding Rna.   PLoS One 9 (11): e111715 2014.11

27. Oda K, Uto H, Kumagai K, Ido A, Kusumoto K, Shimoda K, Hayashi K, Stuver SO, Tanaka Y, Nishida N, Tokunaga K, Tsubouchi H.  Impact of a Single Nucleotide Polymorphism Upstream of the Il28b Gene in Patients Positive for Anti-Hcv Antibody in an Hcv Hyperendemic Area in Japan.   J Med Virol 86 (11): 1877-85 2014.11

28. Yamasaki K, Tateyama M, Abiru S, Komori A, Nagaoka S, Saeki A, Hashimoto S, Sasaki R, Bekki S, Kugiyama Y, Miyazoe Y, Kuno A, Korenaga M, Togayachi A, Ocho M, Mizokami M, Narimatsu H, Yatsuhashi H.  Elevated Serum Levels of Wisteria Floribunda Agglutinin-Positive Human Mac-2 Binding Protein Predict the Development of Hepatocellular Carcinoma in Hepatitis C Patients.   Hepatology 60 (5): 1563-70 2014.11

29. Nagata N, Sakamoto K, Arai T, Niikura R, Shimbo T, Shinozaki M, Aoki T, Kishida Y, Sekine K, Tanaka S, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Noda M, Itoh T, Mizokami M, Uemura N.  Visceral Abdominal Fat Measured by Computed Tomography Is Associated with an Increased Risk of Colorectal Adenoma.   Int J Cancer 135 (10): 2273-81 2014.11.15

30. Nagata N, Sakamoto K, Arai T, Niikura R, Shimbo T, Shinozaki M, Aoki T, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Noda M, Itoh T, Mizokami M, Uemura N.  Visceral Abdominal Obesity Measured by Computed Tomography Is Associated with Increased Risk of Colonic Diverticulosis.   J Clin Gastroenterol [Epub ahead of print]: 2014.11.19

31. Mukai A, Iijima H, Hiyama S, Fujii H, Shinzaki S, Inoue T, Shiraishi E, Kawai S, Araki M, Hayashi Y, Kondo J, Mizushima T, Kanto T, Egawa S, Nishida T, Tsujii M, Takehara T.  Regulation of Anergy-Related Ubiquitin E3 Ligase, Grail, in Murine Models of Colitis and Patients with Crohn's Disease.   J Gastroenterol 49 (12): 1524-35 2014.12

32. Nagata N, Niikura R, Aoki T, Shimbo T, Kishida Y, Sekine K, Tanaka S, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Mizokami M, Uemura N.  Lower Gi Bleeding Risk of Nonsteroidal Anti-Inflammatory Drugs and Antiplatelet Drug Use Alone and the Effect of Combined Therapy.   Gastrointest Endosc 80 (6): 1124-31 2014.12

33. Srilohasin P, Chaiprasert A, Tokunaga K, Nishida N, Prammananan T, Smittipat N, Mahasirimongkol S, Chaiyasirinroje B, Yanai H, Palittapongarnpim P.  Genetic Diversity and Dynamic Distribution of Mycobacterium Tuberculosis Isolates Causing Pulmonary and Extrapulmonary Tuberculosis in Thailand.   J Clin Microbiol 52 (12): 4267-74 2014.12

34. Michikawa T, Inoue M, Sawada N, Tanaka Y, Yamaji T, Iwasaki M, Shimazu T, Sasazuki S, Mizokami M, Tsugane S.  Plasma Isoflavones and Risk of Primary Liver Cancer in Japanese Women and Men with Hepatitis Virus Infection: A Nested Case-Control Study.   Cancer Epidemiol Biomarkers Prev [Epub ahead of print]: 2014.12.26


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